Most prostate most cancers outcomes don’t differ considerably between transgender girls (TGW) and cisgender (CG) males, together with prostate cancer-specific mortality, in line with a examine revealed on-line July 21 in Most cancers.
Margaret Meagher, M.D., from the College of California San Diego Faculty of Drugs in La Jolla, and colleagues in contrast oncological traits and survival outcomes between TGW and CG males with prostate most cancers utilizing knowledge from the Veterans Affairs Informatics and Computing Infrastructure database (1999 to 2020) and the Surveillance, Epidemiology, and Finish Outcomes-Medicare database (2010 to 2017). The teams had been matched in a 5:1 ratio (CG:TGW) based mostly on age, race, yr of prognosis, and Charlson Comorbidity Index rating. Knowledge had been included for 1,194 sufferers: 199 TGW and 995 CG.
The researchers discovered that there have been no vital associations between transgender identification and metastatic presentation, high-risk localized illness, or prostate cancer-specific mortality. There was a big affiliation seen between transgender identification and improved total survival.
“In distinction to earlier research, we didn’t detect worsened prostate most cancers outcomes inside [the transgender] neighborhood,” the authors write. “These conflicting knowledge spotlight the necessity for additional investigation.”
A number of authors disclosed ties to the biopharmaceutical business.
Extra info:
Margaret Meagher et al, Prostate most cancers in transgender girls: A propensity rating–matched evaluation of illness severity and survival, Most cancers (2024). DOI: 10.1002/cncr.35469
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Prostate most cancers outcomes comparable for transgender girls, cisgender males (2024, July 26)
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