New Jersey Sufferers Receiving First-of-Its-Type Catheter Based mostly Pancreatic Most cancers Remedy: © inventory.adobe.com
A crew of oncology consultants at Hackensack Meridian Jersey Shore College Medical Middle, led by Gregory J. Tiesi, M.D., FACS, FSSO, have efficiently handled their first sufferers utilizing RenovoRx’s novel Trans-Arterial Micro-Perfusion (TAMP™) remedy platform. The educational medical heart is the primary hospital in New Jersey to offer TAMP to sufferers.
“We’re utilizing TAMP to offer pinpointed remedy for superior pancreatic most cancers,” mentioned Dr. Tiesi, medical director of Hepatobiliary Surgical procedure at Jersey Shore College Medical Middle (JSUMC). “The position of this particular catheter is completed by our interventional radiologists, it allows chemotherapy to be delivered throughout the arterial wall close to the tumor website within the pancreas with none of the damaging adversarial results that giving the drug to the entire physique might trigger.” Dr. Tiesi additionally famous the tutorial medical heart continues to offer conventional pancreatic most cancers therapies; surgical procedure, chemotherapy, radiation remedy, and different focused therapies, typically together.
“After my analysis, after which going via a number of rounds of chemo- and radiation therapies, my earlier oncologist knowledgeable my household and me that my prospects for a profitable surgical resection weren’t good. And, if I didn’t need to have the surgical procedure, I didn’t have any additional therapy choices, given my physique’s toxicity ranges,” mentioned Christopher Goodwin, of Brigantine, NJ, one of many first sufferers to obtain the remedy. The 51-year-old’s sister Jennifer assisted Christopher to find Dr. Tiesi, so he may obtain a second opinion. “I’m thrilled I’m now capable of obtain this superior remedy and proceed my therapy with Dr. Tiesi at Jersey Shore, near house.”
TAMP, enabled by the RenovoCath®, is a FDA-cleared system (catheter) used to make sure exact therapeutic supply throughout the arterial wall close to the tumor website to wash the goal tumor, whereas probably minimizing a remedy’s toxicities versus systemic intravenous remedy. RenovoCath is being utilized by medical practitioners and is indicated for non permanent vessel occlusion in purposes together with arteriography, preoperative occlusion, and chemotherapeutic drug infusion.
“Implementing TAMP remedy marks a brand new milestone within the customized, precision most cancers care our oncology groups present our sufferers,” mentioned Vito Buccellato, MPA, LNHA, president and chief hospital govt, JSUMC. Buccellato famous that Dr. Tiesi started implanting hepatic artery infusion pumps in sufferers in 2023, for the therapy of cancers throughout the liver, together with; intrahepatic cholangiocarcinoma (IHCC, bile duct most cancers) and colorectal most cancers liver metastases, with out the damaging negative effects seen with systemic chemotherapy.
“The power to enhance the best way we localize and goal therapeutic supply to difficult-to-treat tumors could also be a big step ahead in how we deal with cancers in people, like these with pancreatic most cancers who’ve exhausted different therapy choices,” mentioned JSUMC Surgical Oncologist Anthony Scholer, M.D. FACS, FSSO. “This modern strategy to most cancers therapy not solely has the potential to enhance outcomes for our sufferers but in addition might protect high quality of life, which is our final objective.”
“Jersey Shore stays dedicated to adopting modern therapies like TAMP to boost affected person care and develop entry to modern, exact most cancers therapies,” mentioned Kenneth N. Sable, M.D., MBA, FACEP, regional president, Southern Market, Hackensack Meridian Well being. “Our consultants in oncology are proud to supply this superior possibility as a part of all of the accessible, complete most cancers care providers.” These embody these provided by the Hackensack Meridian John Theurer Most cancers Middle (JTCC) at JSUMC; leukemia care, together with bone marrow transplant, and entry to novel medication or combos of medicine as a part of part I medical trials. “Our sufferers even have entry, via the JTCC, to inpatient stem cell transplantation in addition to the most recent cell remedy therapies, together with chimeric antigen receptor T-cell (CAR-T) remedy,” Dr. Sable famous.
For details about TAMP, name 732-776-4470. For extra details about most cancers care providers, go to www.hackensackmeridianhealth.org/en/providers/cancer-care, or for a free doctor referral, name 844-HMH-WELL.
About RenovoRx, Inc.
RenovoRx (Nasdaq: RNXT) is a life sciences firm growing modern focused oncology therapies and commercializing RenovoCath ® , a novel, U.S. Meals and Drug Administration (FDA)-cleared native drug supply system, concentrating on excessive unmet medical wants. RenovoRx’s patented Trans-Arterial Micro-Perfusion (TAMP™) remedy platform is designed to make sure focused therapeutic supply throughout the arterial wall close to the tumor website to wash the goal tumor, whereas probably minimizing a remedy’s toxicities versus systemic intravenous remedy. RenovoRx’s novel strategy to focused therapy gives the potential for elevated security, tolerance, and improved efficacy, and its mission is to remodel the lives of most cancers sufferers by offering modern options to allow focused supply of diagnostic and therapeutic brokers. Along with the RenovoCath system, RenovoRx can also be evaluating our novel Part III drug-device mixture oncology product candidate (intra-arterial gemcitabine, often known as IAG). IAG is being evaluated beneath a U.S. investigational new drug software that’s regulated by the FDA’s 21 CFR 312 pathway. The investigational IAG makes use of RenovoCath, the Firm’s FDA-cleared drug-delivery system, indicated for non permanent vessel occlusion in purposes together with arteriography, preoperative occlusion, and chemotherapeutic drug infusion. The intra-arterial infusion of chemotherapy, gemcitabine, using the RenovoCath system is presently being evaluated for the therapy of LAPC by the Middle for Drug Analysis and Analysis (the drug division of FDA). IAG by the RenovoCath catheter is presently beneath investigation and has not been accepted for business sale. RenovoCath with gemcitabine obtained Orphan Drug Designation for pancreatic most cancers and bile duct most cancers, which supplies 7 years of market exclusivity upon new drug software approval by the FDA. RenovoRx can also be engaged in implementing commercialization methods using its TAMP expertise and FDA-cleared RenovoCath system as stand-alone system. In December 2024, RenovoRx introduced the receipt of its first business buy orders for RenovoCath units. Moreover, sure of those clients have already initiated repeat orders as RenovoRx works to develop the variety of medical establishments which have initiated the method for RenovoCath buy orders, together with a number of esteemed, excessive quantity Nationwide Most cancers Institute-designated facilities. To satisfy and fulfill the anticipated demand, RenovoRx will proceed to actively discover additional revenue-generating exercise both by itself or in tandem with a medical system business associate. For extra info, go to www.renovorx.com. Comply with RenovoRx on Fb, LinkedIn, and X.
ABOUT HACKENSACK MERIDIAN JERSEY SHORE UNIVERSITY MEDICAL CENTER
Jersey Shore College Medical Middle is a not-for-profit instructing hospital and the one Stage I Grownup and Stage II Pediatric Trauma Middle in Monmouth and Ocean counties. It’s house to Ok. Hovnanian Youngsters’s Hospital. With greater than 1,300 physicians and dental employees in 60 specialty areas, the tutorial medical heart’s crew supplies high-quality care in a patient-centered, environmentally-friendly setting.
Jersey Shore’s medical analysis program and longstanding dedication to medical training is clear via affiliations with Hackensack Meridian Faculty of Drugs and St. George’s College Faculty of Drugs. With greater than 190 residents and fellows in 19 accredited packages, Jersey Shore advances medical information, trains future physicians and supplies the neighborhood entry to promising medical breakthroughs and medical trials. The medical heart is the primary in New Jersey to have implanted a dual-chamber leadless pacemaker and the Micra Transcatheter Pacing System; the world’s smallest pacemaker, and is without doubt one of the elite amenities in Monmouth and Ocean counties to carry out robotic-assisted, minimally invasive Coronary Artery Bypass Graft Surgical procedure and Transcarotid Arterial Revascularization. Lately, Jersey Shore launched a Motion Dysfunction Program, Neuro-Oncology Program, and opened the Dr. Robert H. Harris Neuroscience Remedy heart — a centralized entry level for sufferers to entry an entire array of neuroscience providers. The Middle for Paralysis and Reconstructive Nerve Surgical procedure supplies essentially the most superior therapy choices to assist restore perform in sufferers from all over the world who’ve suffered from stroke, neuropathy, brachial plexus accidents, diaphragm paralysis and different circumstances.
Jersey Shore’s HOPE Tower is a 10-story medical workplace constructing offering a therapeutic outpatient expertise with superior therapy, imaging and lab providers, specialty doctor places of work and a most cancers heart. The most cancers heart contains a vary of modern therapy choices, together with surgical specialties, medical oncology, Cardio-Oncology Program, and essentially the most superior radiation remedy and minimally invasive interventional therapies. Hackensack College Medical Middle’s Organ Transplantation Division supplies transplantation providers and Hackensack Meridian John Theurer Most cancers Middle supplies a bone marrow transplant program and nationally acknowledged blood cancers program.
Jersey Shore College Medical Middle has been ranked by U.S. Information & World Report as a Prime 10 hospital in New Jersey for 11 consecutive years, together with #4 in N.J., #35 within the nation in Obstetrics & Gynecology providers, and high-performing in 15 specialties, procedures/circumstances for 2024-25. Jersey Shore additionally obtained seven consecutive ‘A’ grades for affected person security from The Leapfrog Group. U.S. Information & World Report has ranked Ok. Hovnanian Youngsters’s Hospital, with Hackensack Meridian Joseph M. Sanzari Youngsters’s Hospital, because the #1 Youngsters’s Hospital in N.J. for 3 consecutive years, and nationally ranked in Pediatric Nephrology, Neurology & Neurosurgery, Most cancers and Urology.
Healthgrades acknowledges Jersey Shore as one among America’s 250 Greatest Hospitals (2021-2024), 50 Greatest for Cardiac Surgical procedure (2024), 100 Greatest Hospitals for Stroke Care (2021-2024), 100 Greatest Hospitals for Gastrointestinal Care (2022-2024), 100 Greatest Hospitals for Cardiac Care (2023-2024), and with Excellence Awards in Affected person Security (2024), Neurosciences (2021-2024), Bariatric Surgical procedure (2021-2024), Important Care (2023-2024) and Cranial Neurosurgery (2022-2024). For info, go to www.hackensackmeridianhealth.org.
ABOUT HACKENSACK MERIDIAN HEALTH
Hackensack Meridian Well being is a number one not-for-profit well being care group that’s the largest, most complete and actually built-in well being care community in New Jersey, providing an entire vary of medical providers, modern analysis and life-enhancing care. The community has 18 hospitals and greater than 500 affected person care areas, which embody ambulatory care facilities, surgical procedure facilities, house well being providers, ambulance providers, lifesaving air medical transportation, rehabilitation facilities, pressing care facilities, doctor apply areas, and a health and wellness heart. With greater than 35,000 crew members and seven,000 physicians, Hackensack Meridian Well being is a distinguished chief in well being care philanthropy and dedicated to the well being and well-being of communities all through New Jersey.
The community’s notable distinctions embody having the one #1 ranked grownup and kids’s hospitals in New Jersey, as ranked by U.S. Information & World Report, 2024-25. Hackensack College Medical Middle is nationally-ranked by U.S. Information & World Report in eight specialties. To be taught extra, go to www.hackensackmeridianhealth.org.
