Meta-analyses of gene methylation and smoking conduct in non-small cell lung most cancers sufferers


  • Takeda, Ok., Hida, T., Sato, T., Ando, M., Seto, T., Satouchi, M. et al. Randomized part III trial of platinum-doublet chemotherapy adopted by gefitinib in contrast with continued platinum-doublet chemotherapy in Japanese sufferers with superior non-small-cell lung most cancers: outcomes of a west Japan thoracic oncology group trial (WJTOG0203). J Clin Oncol 28, 753–60 (2010).

    Article 
    CAS 

    Google Scholar
     

  • Pao, W. & Chmielecki, J. Rational, biologically primarily based remedy of EGFR-mutant non-small-cell lung most cancers. Nat Rev Most cancers 10, 760–74 (2010).

    Article 
    CAS 

    Google Scholar
     

  • Chen, W., Zheng, R., Zhang, S., Zhao, P., Zeng, H. & Zou, X. Report of most cancers incidence and mortality in China, 2010. Ann Transl Med 2, 61 (2014).

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Siegel, R., Naishadham, D. & Jemal, A. Most cancers statistics, 2012. CA Most cancers J Clin 62, 10–29 (2012).

    Article 

    Google Scholar
     

  • Byers, L. A. & Rudin, C. M. Small cell lung most cancers: The place can we go from right here? Most cancers (2014).

  • Xie, D., Lan, L., Huang, Ok., Chen, L., Xu, C., Wang, R. et al. Affiliation of p53/p21 expression and cigarette smoking with tumor development and poor prognosis in non-small cell lung most cancers sufferers. Oncol Rep 32, 2517–26 (2014).

    Article 
    CAS 

    Google Scholar
     

  • Tessema, M., Yingling, C. M., Liu, Y., Tellez, C. S., Van Neste, L., Baylin, S. S. et al. Genome-wide unmasking of epigenetically silenced genes in lung adenocarcinoma from people who smoke and by no means people who smoke. Carcinogenesis 35, 1248–57 (2014).

    Article 
    CAS 

    Google Scholar
     

  • Tessema, M., Yu, Y. Y., Stidley, C. A., Machida, E. O., Schuebel, Ok. E., Baylin, S. B. et al. Concomitant promoter methylation of a number of genes in lung adenocarcinomas from present, former and by no means people who smoke. Carcinogenesis 30, 1132–8 (2009).

    Article 
    CAS 

    Google Scholar
     

  • Kwon, Y. J., Lee, S. J., Koh, J. S., Kim, S. H., Lee, H. W., Kang, M. C. et al. Genome-wide evaluation of DNA methylation and the gene expression change in lung most cancers. J Thorac Oncol 7, 20–33 (2012).

    Article 
    CAS 

    Google Scholar
     

  • Yanagawa, N., Tamura, G., Oizumi, H., Endoh, M., Sadahiro, M. & Motoyama, T. Inverse correlation between EGFR mutation and FHIT, RASSF1A and RUNX3 methylation in lung adenocarcinoma: relation with smoking standing. Anticancer Res 31, 1211–4 (2011).

    CAS 
    PubMed 

    Google Scholar
     

  • Nakata, S., Sugio, Ok., Uramoto, H., Oyama, T., Hanagiri, T., Morita, M. et al. The methylation standing and protein expression of CDH1, p16(INK4A) and fragile histidine triad in nonsmall cell lung carcinoma: epigenetic silencing, medical options and prognostic significance. Most cancers 106, 2190–9 (2006).

    Article 
    CAS 

    Google Scholar
     

  • Jiang, H., Solar, M. W., Hefright, B., Chen, W., Lu, C. D. & Zeng, J. Efficacy of hypocaloric parenteral vitamin for surgical sufferers: a scientific evaluate and meta-analysis. Clin Nutr 30, 730–7 (2011).

    Article 

    Google Scholar
     

  • Coory, M. D. Touch upon: Heterogeneity in meta-analysis ought to be anticipated and appropriately quantified. Int J Epidemiol 39, 932 (2010).

    Article 

    Google Scholar
     

  • Gates, P., Jaffe, A. & Copeland, J. Hashish smoking and respiratory well being: consideration of the literature. Respirology 19, 655–62 (2014).

    Article 

    Google Scholar
     

  • Xie, A., Croce, B. & Tian, D. H. Smoking and lung most cancers. Ann Cardiothorac Surg 3, 221 (2014).

    PubMed 
    PubMed Central 

    Google Scholar
     

  • Tan, Q., Wang, G., Huang, J., Ding, Z., Luo, Q., Mok, T. et al. Epigenomic evaluation of lung adenocarcinoma reveals novel DNA methylation patterns related to smoking. Onco Targets Ther 6, 1471–9 (2013).

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Suda, Ok., Tomizawa, Ok., Yatabe, Y. & Mitsudomi, T. Lung cancers unrelated to smoking: characterised by single oncogene dependancy? Int J Clin Oncol 16, 294–305 (2011).

    Article 
    CAS 

    Google Scholar
     

  • Uimonen, Ok., Merikallio, H., Paakko, P., Harju, T., Mannermaa, A., Palvimo, J. et al. GASC1 expression in lung carcinoma is related to smoking and prognosis of squamous cell carcinoma. Histol Histopathol 29, 797–804 (2014).

    PubMed 

    Google Scholar
     

  • Massion, P. P., Zou, Y., Chen, H., Jiang, A., Coulson, P., Amos, C. I. et al. Smoking-related genomic signatures in non-small cell lung most cancers. Am J Respir Crit Care Med 178, 1164–72 (2008).

    Article 
    CAS 

    Google Scholar
     

  • Ling, Q., Shi, W., Huang, C., Zheng, J., Cheng, Q., Yu, Ok. et al. Epigenetic silencing of twin oxidase 1 by promoter hypermethylation in human hepatocellular carcinoma. Am J Most cancers Res 4, 508–17 (2014).

    PubMed 
    PubMed Central 

    Google Scholar
     

  • Lin, R. Ok., Hsieh, Y. S., Lin, P., Hsu, H. S., Chen, C. Y., Tang, Y. A. et al. The tobacco-specific carcinogen NNK induces DNA methyltransferase 1 accumulation and tumor suppressor gene hypermethylation in mice and lung most cancers sufferers. J Clin Make investments 120, 521–32 (2010).

    Article 
    CAS 

    Google Scholar
     

  • Kobayashi, T., Wang, J., Al-Ahmadie, H. & Abate-Shen, C. ARF regulates the soundness of p16 protein through REGgamma-dependent proteasome degradation. Mol Most cancers Res 11, 828–33 (2013).

    Article 
    CAS 

    Google Scholar
     

  • Jarmalaite, S., Kannio, A., Anttila, S., Lazutka, J. R. & Husgafvel-Pursiainen, Ok. Aberrant p16 promoter methylation in people who smoke and former people who smoke with nonsmall cell lung most cancers. Int J Most cancers 106, 913–8 (2003).

    Article 
    CAS 

    Google Scholar
     

  • Beckedorff, F. C., Ayupe, A. C., Crocci-Souza, R., Amaral, M. S., Nakaya, H. I., Soltys, D. T. et al. The intronic lengthy noncoding RNA ANRASSF1 recruits PRC2 to the RASSF1A promoter, lowering the expression of RASSF1A and growing cell proliferation. PLoS Genet 9, e1003705 (2013).

    Article 
    CAS 

    Google Scholar
     

  • Ekim, M., Caner, V., Buyukpinarbasili, N., Tepeli, E., Elmas, L. & Bagci, G. Willpower of O(6)-methylguanine DNA methyltransferase promoter methylation in non-small cell lung most cancers. Genet Take a look at Mol Biomarkers 15, 357–60 (2011).

    Article 
    CAS 

    Google Scholar
     

  • Phrase, B., Lyn-Cook dinner, L. E., Jr, Mwamba, B., Wang, H., Lyn-Cook dinner, B. & Hammons, G. Cigarette smoke condensate induces differential expression and promoter methylation profiles of essential genes concerned in lung most cancers in NL-20 lung cells in vitro: short-term and persistent publicity. Int J Toxicol 32, 23–31 (2013).

    Article 

    Google Scholar
     

  • Evans, T. R. & Kaye, S. B. Retinoids: current position and future potential. Br J Most cancers 80, 1–8 (1999).

    Article 
    CAS 

    Google Scholar
     

  • Moison, C., Senamaud-Beaufort, C., Fourriere, L., Champion, C., Ceccaldi, A., Lacomme, S. et al. DNA methylation related to polycomb repression in retinoic acid receptor beta silencing. FASEB J 27, 1468–78 (2013).

    Article 
    CAS 

    Google Scholar
     

  • Ye, M., Li, D., Zhou, F., Guo, Q. & Xia, B. Epigenetic regulation of death-associated protein kinase expression in main gastric cancers from Chinese language sufferers. Eur J Most cancers Prev 21, 241–6 (2012).

    Article 
    CAS 

    Google Scholar
     

  • Hu, S. L., Kong, X. Y., Cheng, Z. D., Solar, Y. B., Shen, G., Xu, W. P. et al. Promoter methylation of p16, Runx3, DAPK and CHFR genes is frequent in gastric carcinoma. Tumori 96, 726–33 (2010).

    Article 
    CAS 

    Google Scholar
     

  • Kim, J. S., Kim, H., Shim, Y. M., Han, J., Park, J. & Kim, D. H. Aberrant methylation of the FHIT gene in persistent people who smoke with early stage squamous cell carcinoma of the lung. Carcinogenesis 25, 2165–71 (2004).

    Article 
    CAS 

    Google Scholar
     

  • Liu, Y. L., Yang, H. P., Zhou, X. D., Gong, L., Tang, C. L. & Wang, H. J. The hypomethylation agent bisdemethoxycurcumin acts on the WIF-1 promoter, inhibits the canonical Wnt pathway and induces apoptosis in human non-small-cell lung most cancers. Curr Most cancers Drug Targets 11, 1098–110 (2011).

    Article 
    CAS 

    Google Scholar
     

  • Zhang, B., Zhu, W., Yang, P., Liu, T., Jiang, M., He, Z. N. et al. Cigarette smoking and p16INK4alpha gene promoter hypermethylation in non-small cell lung carcinoma sufferers: a meta-analysis. PLoS One 6, e28882 (2011).

    Article 
    ADS 
    CAS 

    Google Scholar
     

  • Liu, W. J., Tan, X. H., Guo, B. P., Ke, Q., Solar, J. & Cen, H. Associations between RASSF1A promoter methylation and NSCLC: a meta-analysis of revealed knowledge. Asian Pac J Most cancers Prev 14, 3719–24 (2013).

    Article 

    Google Scholar
     

  • Murphy, S. E., Park, S. S., Thompson, E. F., Wilkens, L. R., Patel, Y., Stram, D. O. et al. Nicotine N-glucuronidation relative to N-oxidation and C-oxidation and UGT2B10 genotype in 5 ethnic/racial teams. Carcinogenesis 35, 2526–2533 (2014).

    Article 
    CAS 

    Google Scholar
     

  • Siegel, R., Ma, J., Zou, Z. & Jemal, A. Most cancers statistics, 2014. CA Most cancers J Clin 64, 9–29 (2014).

    Article 

    Google Scholar
     

  • Tantraworasin, A., Lertprasertsuke, N., Kongkarnka, S., Euathrongchit, J., Wannasopha, Y. & Saeteng, S. Retrospective research of ALK rearrangement and clinicopathological implications in utterly resected non- small cell lung most cancers sufferers in Northern Thailand: position of screening with D5F3 antibodies. Asian Pac J Most cancers Prev 15, 3057–63 (2014).

    Article 

    Google Scholar
     

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