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Inhibition of NOTCH4 sensitizes FLT3/ITD acute myeloid leukemia cells to FLT3 tyrosine kinase inhibition

NOTCH4 is important for the survival of FLT3/ITD cells and its knockdown sensitizes FLT3/ITD AML cells to FLT3 TKI therapyTo seek for potential...

Backtracking to the long run: unraveling the origins of childhood leukemia

American Most cancers Society. Most cancers Information and Figures, 2019. American Most cancers Society, Inc.; 2019. https://www.most cancers.org/analysis/cancer-facts-statistics/all-cancer-facts-figures/cancer-facts-figures-2019.html.Greaves M. A causal mechanism for...

Ppm1d truncating mutations promote the event of genotoxic stress-induced AML

Pant V, Quintás-Cardama A, Lozano G. The p53 pathway in hematopoiesis: classes from mouse fashions, implications for people. Blood. 2012;120:5118–27.Article  ...

CD22-targeted CAR-T remedy exhibits promising leads to relapsed massive B-cell lymphoma

CAR-T cell remedy, which targets a particular protein on the floor...

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