On the 2025 ASH Annual Assembly, Dr. James Berenson, of the Berenson Most cancers Heart, introduced new findings on a text-based platform known as measurable high quality of life (MQOL). He defined that the purpose was to point out how MQOL can provide physicians real-time perception into how sufferers with myeloma are feeling between visits, serving to clinicians act sooner to help high quality of life.
Berenson stated MQOL allowed his crew to have interaction 58 sufferers every day for the primary month of a three-month research, asking about widespread signs akin to bone ache, tiredness and sleep points. He famous that 85% of sufferers accomplished the assessments — far larger than typical participation in PRO research — as a result of it took underneath three minutes. He added that MQOL helped him spot regarding signs inside 24 hours and intervene rapidly, main to raised outcomes, and hopes this early research encourages wider use of real-time quality-of-life monitoring.
Transcript
What’s going to you be presenting on at this time?
Per our philosophy concerning the significance of high quality of life, we’re presenting at this time at ASH a paper utilizing a brand-new platform to evaluate PRO, or patient-related outcomes, known as measurable high quality of life, or MQOL. This can be a text-based platform that permits simple and fast entry by sufferers to speak knowledge to me, the doctor, on a way more frequent foundation to study what is going on on with them, each importantly to choose up on any clinically important issues and act on them rather more quickly so they do not come out of hand. As I say, learn between the notes or clinic notes. We’re partaking them on daily basis, and it additionally offers a way more correct evaluation of what a affected person goes by way of. When firms are growing medication, they actually know the reality versus, oh, they’re wonderful, they’re not likely wonderful. You are not selecting up on these negative effects.
On this research, we enrolled 58 sufferers, and we adopted them for 3 months, and we engaged them each day for the primary month with this text-based platform, asking a sequence of questions on widespread signs in myeloma, like bone ache and tiredness and issues sleeping — these sorts of issues — and high quality of life. After which we additionally checked out quite a few what’s 10 measurements of what is known as quality-of-life assessments. And in that research, we discovered that 85% of sufferers bought on board and accomplished the evaluation. That is unprecedented. These research are normally 15 to twenty%, and these have been even sufferers who have been doing effectively who stated, that is simple, I will do it. It took lower than three minutes, simple to get the info, and inside 24 hours if one thing’s gone incorrect — increase — I am on with the affected person, and I will change it quickly and have an effect on a extra optimistic final result for the affected person.
So that is the primary such research and hopefully will result in many others, which is able to enable a extra real-time evaluation of what actually occurs to your affected person and permit me to have an effect on a greater final result as a result of I will act on issues which might be clinically important that I might have by no means seen as a result of I wasn’t capable of learn between the notes. However now we are able to.
Reference
- “Remodeling affected person outcomes in a number of myeloma by way of real-time, text-based monitoring of signs and high quality of life: Outcomes from the MQOL feasibility research” by Dr. James Berenson, Oral Summary Session, ASH Annual Assembly, introduced Dec. 6, 2025
Transcript has been edited for readability and conciseness.
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